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Saturday, 21 December 2013

How to choose a column ?


  • Suitability for a specific application
    • The column must do the job
    • If already using a different column the new column should provide a benefit in performance or durability
  • Reproducibility of the result from column to column and Lot to Lot
    •  Reliable performance
  • Stability & Life time of the column
    • Less column changes will cause less instrument down time and therefore more sample can be run
  • Compliance with official methods that might need to be followed
    •  In case the customer needs to follow official methods like Pharmacopoeia, EPA, DIN or other local
  • LC/MS suitability (for LC/MS user)
    • Low Bleed of a column to reduce background signal/interference. This makes the identification in the MS easier.

Waters column

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